Starstat – Ez


Drug Name:

Ezetimibe 10mg + Simvastatin 20mg Tablets

Category:

International Brand: Vytorin

Details


Ezetimibe 10mg + Simvastatin 20mg Tablets are a Dyslipidaemic Agent. It contains ezetimibe, a related phytosterol absorption and selective inhibitor of intestinal cholesterol. Simvastatin is an HMG-CoA reductase inhibitor. This medicine is available by the name of Vytorin in international pharmacies. In India, it is known by the name Starstat – Ez.

Purpose:

  • These tablets are indicated as adjunctive therapy for the reduction of elevated total cholesterol (total-C).
  • It increases high-density lipoprotein cholesterol (HDL-C) in patients suffering from primary hypercholesterolemia.
  • Low-density lipoprotein cholesterol (LDL-C) is also reduced by Vytorin drug.
  • Elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia are treated with this medicine.

Mechanism:

Starstat – Ez reduces higher levels of total-C, TG, LDL-C, non-HDL-C, and Apo B, and increases HDL-C through dual inhibition of synthesis and cholesterol absorption.

 

Dosage:

  • Strictly as prescribed by your doctor.
  • The recommended dosage of Ezetimibe 10mg + Simvastatin 20mg Tablets for effective results is 10 mg once daily.
  • The maximum dose to be consumed in a day is 20 mg.

Side effects:

  • Common side effects of Starstat – Ez are nausea, vomiting, fatigue, stomachache, dizziness, headache, lightheadedness, and diarrhea.
  • A rare but serious effect includes mild memory problems.
  • A serious condition of rhabdomyolysis and autoimmune therapy (muscle problems) might occur, in rare cases.
  • Serious side effects of this drug are dark urine, trouble breathing, yellowing of the skin, liver problems, change in the amount of urine, swelling of face or throat among others.

Precautions and measures:

  • Make sure you have a low-fat diet during this medication.
  • Do regular exercise.
  • If you have had a medical history of alcohol use, kidney disease, or liver problems, inform your doctor about the same before starting with these tablets.
  • It is absorbed via the lungs and body, and must not be used by pregnant ladies, as it can harm the unborn baby.
  • The safety of Ezetimibe 10mg + Simvastatin 20mg Tablets have not been established in children under the age of 10 years.
  • If you experience muscle problems that do not go away, consult your doctor as early as possible.
  • Do not crush, break, or split the tablet.
  • Do not increase, decrease or stop taking the dose at your own convenience.

 

Interactions:

  • Some medicines that can interact with Starstat – Ez and produce negative effects are Warfarin, Gemfibrozil, Danazol, Cyclosporine, and Daptomycin.

Other medicines can result in complete removal of Ezetimibe 10mg + Simvastatin 20mg Tablets such as Boceprevir, Colchicine, Ketoconazole, Ritonavir among others.