Janumet


Drug Name:

Sitagliptin 50mg + Metformin 1000mg Tablets

Category:

International Brand: Janumet

Details


Sitagliptin 50mg + Metformin 1000mg Tablets are Antidiabetic agents. They are an inhibitor of the dipeptidyl peptidase-4 enzyme. This medicine is known by the name of Janumet, both in India, as well as internationally.

Purpose:

  • Sitagliptin 50mg + Metformin 1000mg Tablets are used to treat Type 2 Diabetes Mellitus by lowering and balancing the blood sugar level.
  • Other problems like blindness, kidney damage, loss of limbs, nerve problems, and sexual function problems are also controlled by this medication.

Mechanism:

  • Janumet tablets slow down the action of certain enzymes that break down food into sugars. Because of this, the digestion of carbohydrates slows down and prevents your blood sugar level from rising high after you eat.
  • More insulin is produced in the pancreas, and excess sugar is reduced in the liver.

Dosage:

  • Strictly as prescribed by your doctor.
  • The treatment varies from person to person, based on their age, health condition, and response to the treatment.
  • The recommended dosage for effective results is one dose of Sitagliptin 50mg + Metformin 1000mg Tablets daily.

 

Side effects:

  • Common side effects of Janumet medicine are nausea, flatulence, diarrhea, stomachache, sore throat, stuffy nose, respiratory tract infection, and vomiting.
  • Serious side effects are swelling in the stomach, yellowing of skin or eyes, swelling of skin, and pneumatosis cystoides intestinalis.
  • A rare but serious condition of lactic acidosis might develop, where the lactic acid in the blood increases. Consult your doctor immediately if this happens.
  • Hypoglycemia (low blood sugar level).

 

Precautions:

  • People suffering from diabetic ketoacidosis should not consume these tablets.
  • Patients with liver cirrhosis or other liver disorders are advised not to undergo this medication as it may only worsen the situation.
  • Low blood sugar can develop if people who are on insulin or sulfonylurea take Janumet.
  • If you have had a medical history of inflammatory bowel disease, partial intestinal obstruction, colonic ulceration, or if you’re predisposed to intestinal obstruction, inform your doctor before starting with this treatment.
  • If your blood glucose levels rise up, consult your doctor immediately.
  • Maintain a proper diet and an exercise program.
  • Pregnant and lactating women should undergo this medication under the strict guidance of their doctor.
  • To lower your chances of an upset stomach, take this capsule with food

Interactions:

Some medications can affect the blood sugar level, and increase it rapidly, such as metoprolol, and propranolol. Therefore, avoid taking them with Sitagliptin 50mg + Metformin 1000mg Tablets.