Irovel – H

Details

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Irbesartan 150mg + Hydrochlorothiazide 12.5mg Tablets belong to the class of Angiotensin Receptor Blockers. It is known by the name of Avalide internationally. In India, it is known by the name Irovel – H. This is a combination of two medicines Irbesartan and Hydrochlorothiazide, respectively.

 

Purpose:

• Avalide tablets are indicated to treat hypersensitivity (high blood pressure).
• It lowers the risk of strokes in patients with an enlarged heart.
• It is also used in the treatment of heart failure, renal protection in type 2 diabetic patients with proteinuria, and reducing cardiovascular morbidity.

 

Mechanism:

Irovel – H tablets and their active metabolite block the aldosterone-secreting and vasoconstrictor effects of angiotensin. It allows easy and smooth flow of blood to all organs inside the body, by relaxing the blood vessels. Being a water pill, it allows the body to make more urine, and get rid of extra water and salt from the body.

 

Dosage:

• Strictly as prescribed by your doctor.
• It is taken by mouth either after having a meal or an empty stomach.
• The dosage of these tablets depends on your medical condition and response to the treatment.
• If you are also taking drugs to lower your cholesterol, take this at least 4 to 6 hours before or after that medication.
• Take this medication regularly at the same time to get the most benefit of it.
• The recommended dosage of Irbesartan 150mg + Hydrochlorothiazide 12.5mg Tablets for effective results is 1 tablet, once daily.
• Some patients might receive an additional benefit by increasing the dose to 100 mg, once daily.
• In patients with heart failure, should take 12.5 mg once daily.
• In patients with Type 2 diabetes should take 50 mg once daily.

 

Side effects:

• Common side effects of Irovel – H tablets are nausea, dizziness, vomiting, sleepiness, lightheadedness, diarrhea, and fever.
• Serious side effects of Irbesartan 150mg + Hydrochlorothiazide 12.5mg Tablets are anemia, depression, somnolence, paresthesia, migraine, vertigo, tinnitus, urticaria, impotence, edema, dyspnea, atrial fibrillation, syncope, and sleep disorders.
• If any of the above-mentioned side effects persist for long, consult your doctor right away.

 

Precautions and measures:

• In patients being treated with a high dose of diuretics along with Irbesartan 150mg + Hydrochlorothiazide 12.5mg Tablets, might face symptomatic hypotension.
• If you have had a medical history of liver disease, or dehydration, inform your doctor before starting with this medication.
• Limit your intake of alcohol and marijuana as it can lead to extreme dizziness and sleepiness.
• Do not crush, break, or split the tablet.
• Do not use expired medication.
• Store them at room temperature.
• Keep them away from kids and pets.
• Do not increase or decrease the dosage at your own ease.
• Get regular tests of creatinine, urea, and potassium in your blood.
• Rise slowly if you’ve been lying or sitting for quite a long time.
• Pregnant women should avoid this medication in their second or third trimesters.

 

Interactions:

Drugs that can interact with Irovel – H tablets and produce negative effects are Aliskiren, Benazepril, Lithium, Drospirenone, and Lisinopril. Hence, they should be avoided.