Sprycel


Drug Name:

Dasatinib 50mg, 70mg Tablets

Category:

International Brand: Sprycel

Details


Dasatinib 50mg, 70mg Tablets belong to the category of anti-cancer drugs and help decrease tumour cell proliferation in vitro. Sprycel is the universal name of this drug by which it is available in the medical market.

Purpose:

  • It stops or slows down the growth of cancer cells.
  • Sprycel inhibits the tumor growth of DTC, HCC, and RCC human tumor xenografts in immunocompromised mice.
  • Chronic Myeloid Leukemia-CML is treated with this drug.
  • Dasatinib 50mg, 70mg Tablets are also used to treat Acute Lymphoblastic Leukemia-ALL

Dosage:

  • As prescribed by your physician/doctor.
  • The recommended dosage for effective results is 50 mg tablets twice daily, without food, at least 1 hour before the meal.
  • When dose reduction seems necessary in some conditions, it should be reduced to 50 mg once daily.
  • Patients suffering from Chronic Myeloid Leukemia and Acute lymphoblastic Leukemia should intake 200 mg once daily of Nexavar tablets.

Side effects:

  • Common side effects of Dasatinib 50mg, 70mg Tablets are weight loss, vomiting, nausea, dry skin, hair loss, mouth sores, loss of appetite, tiredness, changes in taste, or voice.
  • It is indicated to increase your blood pressure.
  • If you experience any signs of constipation, overactive thyroid, slow heartbeat, unusual weight loss, or cold intolerance, visit your doctor right away, before the situation worsens.
  • Other side effects of Sprycel include fainting, bloody stools, swelling, trouble in breathing, back pain, changes in vision, unusual pain, jaw pain, muscle spasms, dark urine, yellowing of the skin, sore throat, easy bruising among others.
  • Gastrointestinal perforation
  • Drug-induced hepatitis
  • Hemorrhage
  • Cardiac ischemia
  • WT interval prolongation

Precautions and measures:

  • Keep a regular check on your blood pressure while you’re on medication for Sprycel tablets.
  • The safety of this drug in children has not been established.
  • If you have had a medical history of coronary artery disease, high blood pressure, aneurysm, break in the aorta, liver disease, heart attack, or any recent injury, inform your doctor.
  • Low levels of magnesium and potassium in the blood.
  • This medication can result in delayed healing of wounds.
  • If you’re planning to have surgery, during the tenure of this drug, discuss the risks and benefits with your doctor.
  • Pregnant women are advised not to consume these tablets as it is absorbed through lungs and skin and can harm the unborn baby.

Breastfeeding is not recommended during the tenure of Dasatinib 50mg, 70mg Tablets and for 2 weeks after discontinuing the drug.

Frequently Asked Questions

1. What is Sprycel (Dasatinib) used for?

Sprycel contains dasatinib, a tyrosine kinase inhibitor used in the treatment of Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). Its approved uses include newly diagnosed chronic-phase CML and certain CML or Ph+ ALL cases with resistance or intolerance to previous therapy.

2. How does Sprycel (Dasatinib) work?

Sprycel works by inhibiting specific tyrosine kinases involved in the growth and survival of leukemia cells, including BCR-ABL. By blocking these signaling pathways, dasatinib helps inhibit the proliferation of certain leukemia cells. Treatment should be prescribed and monitored by a qualified healthcare professional.

3. What strengths of Sprycel tablets are available?

Sprycel tablets are available in 20 mg, 50 mg, 70 mg, 80 mg, 100 mg, and 140 mg strengths. The appropriate strength and dosing schedule depend on the patient’s condition, treatment response, age, and other clinical factors.

4. How is Sprycel administered?

Sprycel is an oral tablet that is generally taken once daily, with or without food, according to the prescribed regimen. The tablets should be swallowed whole and should not be crushed, cut, or chewed. Adult dosing varies by indication and disease phase, so treatment should follow the prescribing healthcare professional’s instructions.

5. Can international buyers source Sprycel from Lotus International?

Lotus International supplies oncology medicines to international importers, pharmaceutical distributors, wholesalers, hospitals, and procurement organizations. Buyers seeking Sprycel or other oncology medicines can contact Lotus International regarding product availability, quantities, packaging, export documentation, and international supply requirements. Lotus states that it accepts bulk orders for oncology medicines from India.